The Power of Functional Resins in Organic Synthesis by Fernando Albericio, Judit Tulla-Puche
By Fernando Albericio, Judit Tulla-Puche
Whereas many books conceal good part synthesis and combinatorial synthesis, this one is exclusive in its particular insurance of the opposite points of solid-phase synthesis. As such, it comprises every little thing you want to comprehend -- from supported reagents, to scavengers, resins, and the synthesis of biomolecules and typical products.
a useful better half for all chemists and biochemists operating in collage examine and undefined.
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A popular strategy has been to imprint a transition state analog to obtain a polymer that reduces the activation energy of the reaction. Catalytically active groups are often included in the polymer network. This approach has been applied towards ester and amide hydrolysis reactions [245, 246]. Examples of other reactions where MIPs have been utilized as enzyme mimics are isomerization [247], transamination [248], Diels–Alder reaction [249], β-elimination [250] and regioselective cycloaddition [251].
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